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Assessment of the Correlation Between MRI Findings and Levels of Prolactin and TSH Among Pituitary Adenoma Patients

    Authors

    • Basma Talib Nasser 1
    • Muna Abdulghani Zghair 2

    1 Diagnostic Radiology, Al-Hindiyah Teaching Hospital /Karbala, Iraq.

    2 Diagnostic Radiology, College of Medicine, Al-Mustansiriyah University, Baghdad, Iraq.

,

Document Type : Research Paper

10.52573/ipmj.2024.182812
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Abstract

BACKGROUND:
Pituitary adenomas are tumors of the anterior pituitary. Most pituitary tumors are slow-growing and benign. They are classified based on size or cell of origin. Pituitary adenoma can be described as microadenoma, macroadenoma, and giant tumors based on size.
OBJECTIVE:
 the present study aimed to assess the correlation between MRI findings and levels of prolactin and thyrotropin  in addition to other characteristics of the patients.
PATIENTS AND METHODS: 
An observational correlation study design conducted at Al-Yarmouk Teaching Hospital in the Department of Radiology from 1st of January 2021 through December 2021. The current study involved 101 patients as (22 males) and (79 females) (age ranging from 15- 60 years) as an outpatient with abnormal hormonal assay on lab investigations. 
RESULTS:
Patients with microadenomas and macroadenomas were significantly older than those with normal findings, the mean age was 35.6±8.7 years, 40.6±11 years and 31.2±10.6 years, respectively, (P. value <0.05). Overall pituitary adenomas (micro and macro adenomas) were more frequent in females than males compared to normal findings, (P. value <0.05). Microadenomas were significantly more frequent than macroadenomas in obese (BMI=25-35 ) patients, 29.2% vs. (0%), respectively.
CONCLUSION:
Neuroimaging is an essancial method for evaluation of pituitary adenoma , Pituitary microadenomas  more frequent in young adult , female patients with significant correlation to elevated  prolactin levels. Macroadenomas  more frequent in older , obese female patients.
 

Keywords

  • Pituitary adenoma
  • neuroimaging
  • serum prolactin
  • thyroid stimulating hormone(thyrotropin)
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References
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Iraqi Postgraduate Medical Journal
Volume 23, Issue 1
January 2024
Page 113-119
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APA

Nasser, B., & Zghair, M. (2024). Assessment of the Correlation Between MRI Findings and Levels of Prolactin and TSH Among Pituitary Adenoma Patients. Iraqi Postgraduate Medical Journal, 23(1), 113-119. doi: 10.52573/ipmj.2024.182812

MLA

Basma Talib Nasser; Muna Abdulghani Zghair. "Assessment of the Correlation Between MRI Findings and Levels of Prolactin and TSH Among Pituitary Adenoma Patients". Iraqi Postgraduate Medical Journal, 23, 1, 2024, 113-119. doi: 10.52573/ipmj.2024.182812

HARVARD

Nasser, B., Zghair, M. (2024). 'Assessment of the Correlation Between MRI Findings and Levels of Prolactin and TSH Among Pituitary Adenoma Patients', Iraqi Postgraduate Medical Journal, 23(1), pp. 113-119. doi: 10.52573/ipmj.2024.182812

VANCOUVER

Nasser, B., Zghair, M. Assessment of the Correlation Between MRI Findings and Levels of Prolactin and TSH Among Pituitary Adenoma Patients. Iraqi Postgraduate Medical Journal, 2024; 23(1): 113-119. doi: 10.52573/ipmj.2024.182812

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