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Risk Factors of Ischemic stroke in COVID-19 patients

,

Document Type : Research Paper

Abstract

Background: The Coronavirus Disease 2019 (COVID-19), an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), has become one of the worst pandemics in this century. COVID-19 may increase the risk of acute ischemic stroke similar to the increased risk of 3.2-fold to 7.8-fold seen within the first 3 days after other respiratory tract infections.

Aim: To have the ability of predicting risk of stroke development in COVID

19 patients by relaying on variable parameters involving clinical and inflammatory markers.

Methods and materials: A case control study conducted in Baghdad, the capital of Iraq at Baghdad teaching Hospital, in a period from March 2021 till August 2021.the study included 90 patients tested positive for COVID-19 infection.

Results: The mean age of participants was 58.2 ± 15.6 years (range 22 – 88 years old). The mean age across group A was 65.4 years which was significantly higher than group B age (p=0.0001). Regarding gender, males were representing 53% and 46% of group A and B respectively. Regarding the severity, no mild cases was observed among group A patients (p=0.001). Regarding risk factors, hypertension, DM, history of CVD, smoking, and were associated significantly with developing ischemic stroke (p<0.05). Also, developing respiratory failure was associated with development of ischemic stroke (p=0.002). Regarding inflammatory markers, D-Dimer and ferritin levels were significantly higher among group A patients in comparison to group B patients (p<0.05). While, LDH did not demonstrated significant difference between both groups (p=0.14).

Conclusion: Age, hypertention, D.M, somking, Hx of CVD, Severity of COVID-19 infection, respiratory failure and D-Dimer, ferritin levels were significantly higher among COVID patients who developed stroke. LDH did not demonstrated significant difference.

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Iraqi Postgraduate Medical Journal
Volume 23, Issue 3
July 2024
Page 331-337
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