Abstract

ABSTRACT:
BACK GROUND:
To evaluate the value of diffusion weighted magnetic resonance imaging (DWMRI) in
detection and T- staging of bladder carcinoma and correlation with histopathological staging.
PATIENTS AND METHODS:
An analytic prospective study was conducted at the MRI units of Al-yarmook teaching hospital
in the period from January of 2015 to December 2015, 42patients (36male and 6 female)
presented with hematuria (40 patients ) and 2 patients presented with pelvic pain were enrolled
prospectively ,they underwent conventional magnetic imaging(MRI) and diffusion weighted
MRI using 3 tesla MR units (Achieva ; Philips medical systems, the Netherlands).
Diffusion weighted images were obtained using a single shot echo planar imaging sequence EPI
with b value 0,500sec/mm2.ADC value map was reconstructed and mean ADC value were
measured in 42 patients .and histological examination was done to all patients.
RESULTS:
Correlation between standard MR staging of bladder carcinoma and histopathological results
revealed that 17 patients (40%) had the same T -staging while 17 patients(40%) over staged.
DWI and ADC values were able to declare the cause of overstating by discrimination between
tumoral tissue and peritumoral inflammation. Statistically significant difference is found between
ADC value of bladder tumor and those of urine.
CONCLUSION:
Diffusion weighted MR imaging at 3 tesla is new and good imaging modalities for detection and
staging of bladder carcinoma, , without using contrast media, so can used in patient with renal
impairment or contrast media allergy