Abstract

ABSTRACT:
BACKGROUND:
Wilms tumor is one of the most common nephrologic paediatric tumors, a retrospective study of 24 patients had wilms tumor were reviewed from clinical and epidemiological point in the oncology unit of Child Central Teaching Hospital for the period (June 1st 2004 to June 1st 2010).
OBJECTIVE:
To find out the main clinical features, diagnosis,treatment modalities and outcome of children with wilms tumor admitted to central teaching hospital.
PATIENTS AND METHODS:
Records of 24 cases were collected and analyzed as aretrospective study done in oncology unit in central teaching hospital over 6 year period from June 1st2004 to June 1st 2010
RESULTS:
Patients included 13 males and 11 females; the mean age at presentation for males was 3.7 years and 2.5years for females,male to female ratio was 1.18:1 .
Asymptomatic abdominal mass was the most common presenting feature in 24 patients (100%) followed by haematuria in 7patients (29.2%), hypertension in 3 patients (12.5%), congenital anomaly(which was hemihypertrophy of the Lt. side) in 1patient (4.2%) & other presenting features including: fever, weight loss, nausea, vomiting, abdominal pain in 15 patients (62.5%).
The tumor was left sided in 14 (58.3%) patients, right sided in 8 (33.4%) patients & bilateral in 2 patients (8.4%).
Stage III wilms tumor was the commonest histopathological type in 7 patients (29.2%).
The overall survival was (41.6%); the overall mortality rate was (16.7%); infection and sepsis were the main causes of death in 2 patient (8.3%).We had 4 patients died ,2 of them due to infection &sepsis , other 2 patients cause of death not reported.
CONCLUSION:
The study showed the clinicodemographic fates of patient with wilms tumor were similar to other studies but still infection &sepsis were common causes of death in advanced stages because of delayed referral in most cases.