Abstract

ABSTRACT:
BACKGROUND:
Approximately one in four women will have an early pregnancy failure during her lifetime. In pregnant women or in their partners, human papillomavirus infection can be considered as a risk of preterm birth, miscarriages and virus transmission to the newborn.
OBJECTIVE:
To disclose the prevalence of high risk human papillomavirus infection in women suffering from spontaneous miscarriage .
PATIENTS AND METHODS:
A case - control study included 100 pregnant women ,age (20-42 years old) ,50 full term pregnant )Gestation age 37-40 week) delivered viable full term pregnancy, and 50 pregnant women experienced spontaneous miscarriage (Gestation age 8-24week), cervical swab was done in the labor ward of Al-Yarmouk Teaching Hospital from all participants, and the samples were taken to a private lab for high risk human parvovirus detection. The study period was from 1st of March to 30th of November 2017.
RESULTS:
The overall prevalence of high risk human papillomavirus is 7%, the highest proportion of study patients with high risk human papillomavirus infection ended with miscarriage (71.4%), while in those with viable full term pregnancy were (28.6%). A number of risk factors which increased prevalence of high risk human papillomavirus hrHPV infection were detected as previous history of miscarriage, smoking, and history of oral contraceptives use.
CONCLUSIONS:
High risk human papillomavirus prevalence was higher in pregnancy with spontaneous miscarriage compared to women experience a normal full term pregnancy.
KEYWORDS: Miscarriage, high risk human papillomavirus (hrHPV), Pregnancy.