Abstract

ABSTRACT :
BACKGROUND:
GGT ( gamma- glutamyl transferase ) enzyme is found on the surface of various cells and plays a
role in the catabolism of glutathione which is known as one of the major anti oxidants,
OBJECTIVE:
Of this study : was to emphasize the changed GGT values as anew biochemical marker for acute
coronary syndrome
METHOD:
Type of study is a case – control study. The study population: We enrolled 50 patients with acute
coronary syndrome who had been admitted to ccu unit in Merjan Teaching hospital, measurement
of serum gamma- glutamyl transferase level using gamma- glutamyl transferase was measured by
enzymatic method using the Abbott Architect C16000 autoanalyser and compared to the serum
gamma- glutamyl transferase level of the 50 control group , the period of the study is 6 months.
Both groups will under go an exclusion criteria for all causes that may lead to a high gammaglutamyl
transferase level mainly hepatobiliary diseases , alcohol history, diabetes mellitus , and
drugs that affect the gamma- glutamyl transferase level .
RESULT:
Of the study: showed that gamma- glutamyl transferase level is elevated in all patients with
documented acute coronary syndrome after exclusion of other factors which cause elevation of
gamma- glutamyl transferase in comparism with the control .
CONCLUSION & RECOMMENDATION:
This study depicts association of gamma- glutamyl transferase with acute coronary syndrome in
population from Babylon governorate & Larger community based studies are needed to establish
the role of gamma- glutamyl transferase in development of the commonly mentioned risk factors
of acute coronary syndrome. We recommend the use of GGT as a biomarker within the 4 days
events of acute coronary syndrome .