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Value of Strain Ratio in the Assessment of Solitary Thyroid Nodules

,

Abstract

BACKGROUND:
Ultrasound elastography (UE) is widely used in the diagnosis of thyroid diseases.
OBJECTIVE:
to evaluate the diagnostic utility of elastography stain ratio in the assessment of solid solitary thyroid nodules.
PATIENTS AND METHODS:
a cross-sectional study was conducted on 65 selected patients with solid solitary thyroid nodules discovered on Ultrasound (U/S) examination. The study was conducted in the U/S unit of medical college/ Al-Nahrain university and U/S unit of Al-Imamein Al-Kadhimein Medical city in Baghdad during the period from February 2018 to October 2019. U/S findings (size, shape and echogenicity of the nodules, presence of calcification, elastography findings and measurement of stain ratio), and histopathological results of the FNA.
RESULTS:
the final histopathological diagnosis of the 65 thyroid lesions revealed 46 (71%) benign and 19 (29%) malignant. Of the 19 malignant nodules; 12 were papillary carcinoma and 7 were follicular carcinoma. The mean age of the patients was 43.7 ±11.7 years (range 28 - 60) years, 50 (77%) of them were female and 15 (23%) were male, male: female ratio is 5:1. Strain ratio (SR) of Benign nodules was lower than that of malignant nodules (1.95±0.62 versus 6.11±3.4) and this difference was statistically significant (P- value <0.001. Best SR Cutoff - value was (>2.6) with a sensitivity of 100% & specificity of 86.4% (a higher value was more indicative of malignancy).
CONCLUSION:
SR in a good parameter to aid differentiating benign from malignant solitary thyroid nodule. SR is higher in malignant thyroid nodules.
 

Keywords

References

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Iraqi Postgraduate Medical Journal
Volume 19, Issue 4
December 2020
Page 297-303
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