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Evaluation of Endplate Failure in Lumbar Disc Prolapse and Their Clinical Outcome Correspondence

    Author

    • Mazin S. Mohammed Jawad

    AL-Imamein Al-Kadhemein Medical City, Baghdad/ Iraq.

,
10.52573/ipmj.2023.179280
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Abstract

BACKGROUND:
Endplate lesions connect in lumbar disc herniation (LDH) evolution, yet correlated clinical course scarcely comprehended.
AIM OF STUDY:
To examine the varieties of endplate failure (EPF) in LDH and their clinical outcome correspondence. 
PATIENTS AND METHODS:
A study of sixty-seven cases that have single-level LDH conducted. Magnetic Resonance Imaging (MRI) and computed tomography (CT) scans distinguish EPF. Twenty-five patients have  a laminectomy, and forty-two managed conservatively. Pursue of pain scores and clinical outcomes.
RESULTS:
Endplate pathology remarked in 65(97.01%), osseous endplate breakdown (Osseous failure) in 48(73.8%), and confined cartilaginous endplate lesions in 17 patients (26.2%). The group with bone failure possesses comparable pain and outcome scores yet worse neurological shortfall at the primary assessment. The clinical picture ameliorates in all groups, though the resurrection was minor in non-operative osseous failure cases.
CONCLUSION: 
Endplate lesions are usually associated with symptomatic LDH. Osseous failure attendance progresses the neurological deficit and lessens the odds of rehabilitation with non-operatively planned cases.  The fat-suppressed 3-dimensional fast spoiled gradient (3D FSPGR) mode of MRI efficiently uses for endplate ailment apprehension in the herniated disc.
 

Keywords

  • lumbar disc herniation
  • Endplate failure
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References
  1. Madan Mohan Sahoo. Significance of Vertebral Endplate Failure in Symptomatic Lumbar Disc Herniation. Global Spine Journal. 2017;7:230-38.
  2. Fields, A.J., Battié, M.C., Herzog, R.J. et al. Measuring and reporting of vertebral endplate bone marrow lesions as seen on MRI (Modic changes): recommendations from the ISSLS Degenerative Spinal Phenotypes Group. Eur Spine J. 2019;28: 2266–74. https://doi.org/10.1007/s00586-019-06119-6.
  3. Zehra, Bow, Lotz, J.C. et al. Structural vertebral endplate nomenclature and etiology: a study by the ISSLS Spinal Phenotype Focus Group. Eur Spine J. 2018; 27: 2–12. https://doi.org/10.1007/s00586-017-5292-93.
  4. Brzuszkiewicz-Kuźmicka G, Szczegielniak J, Bączkowicz D. Age-related changes in shock absorption capacity of the human spinal column. ClinIntervAging.2018;13:987-993.https://doi.org/10.2147/CIA.S156298
  5. Broom ND, Thambyah A. References. In: The Soft–Hard Tissue Junction: Structure, Mechanics and Function. Cambridge: Cambridge University Press; 2018: 353–82.
  6. Yoon Nae Seo. The Characteristics and Incidence of Posterior Apophyseal Ring Fracture in Patients in Their Early Twenties With Herniated Lumbar Disc. Neurospine 2018;15:138-43.
  7. Abbas J, Hamoud K, Peled N, Hershkovitz I. Lumbar Schmorl's Nodes and Their Correlation with Spine Configuration and Degeneration. Biomed Res Int. 2018;2018:1574020. Published 2018 Nov 7. doi:10.1155/2018/1574020.
  8. Fields AJ, Ballatori A, Liebenberg EC, et al. Contribution of the endplates to disc degeneration. Curr Mol Biol Rep. 2018;4:151-160. doi:10.1007/s40610-018-0105-y.
  9. Sahoo MM, Mahapatra SK, Kaur S, et al. Significance of Vertebral Endplate Failure in Symptomatic Lumbar Disc Herniation. Global Spine J. 2017;7:230-38. doi:10.1177/2192568217694142.
  10. Norihiro Nishida, Tsukasa Kanchiku, Daigo Nakandakari, et al. Analysis of stress application at the thoracolumbar junction and influence of vertebral body collapse on the spinal cord and cauda equina. Experimental And Therapeutic Medicine. 2018;15:1177-84.
  11. Pronin S, Koh CH, Bulovaite E, et al. Compressive Pressure Versus Time in Cauda Equina Syndrome: A Systematic Review and Meta-Analysis of Experimental Studies. Spine. 2019;44:1238-47. doi:10.1097/BRS.0000000000003045.
  12. Lama, P., et al. Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype. Cell Death Discov.2019; 5:154. https://doi.org/10.1038/s41420-019-0233-z.

 

 

 

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Iraqi Postgraduate Medical Journal
Volume 22, Issue 1
January 2023
Page 57-65
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APA

Mohammed Jawad, M. (2023). Evaluation of Endplate Failure in Lumbar Disc Prolapse and Their Clinical Outcome Correspondence. Iraqi Postgraduate Medical Journal, 22(1), 57-65. doi: 10.52573/ipmj.2023.179280

MLA

Mazin S. Mohammed Jawad. "Evaluation of Endplate Failure in Lumbar Disc Prolapse and Their Clinical Outcome Correspondence". Iraqi Postgraduate Medical Journal, 22, 1, 2023, 57-65. doi: 10.52573/ipmj.2023.179280

HARVARD

Mohammed Jawad, M. (2023). 'Evaluation of Endplate Failure in Lumbar Disc Prolapse and Their Clinical Outcome Correspondence', Iraqi Postgraduate Medical Journal, 22(1), pp. 57-65. doi: 10.52573/ipmj.2023.179280

VANCOUVER

Mohammed Jawad, M. Evaluation of Endplate Failure in Lumbar Disc Prolapse and Their Clinical Outcome Correspondence. Iraqi Postgraduate Medical Journal, 2023; 22(1): 57-65. doi: 10.52573/ipmj.2023.179280

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