Abstract

BACKGROUND:
A stroke or cerebrovascular accident is defined as an abrupt onset of a neurologic deficit that is attributable to focal vascular cause. Hyperglycemia is a well-known predictor of poor outcomes in patients with acute ischemic stroke. Admission hyperglycemia has been associated with poor functional outcomes and increased mortality in patients with acute ischemic stroke.
OBJECTIVE:
To evaluate the HbA1C level in patient with ischemic stroke and its severity.
PATIENTS AND METHODS:
A cross-sectional study conducted at Baghdad teaching hospital, Baghdad, Iraq during a period from October 2020 to Feb 2021. The study included 50 patients who met the inclusion criteria, as well as,              50 individual (No stroke at time of data collection) as control group.
RESULTS:                                                    
The mean age of patients was 63.8 ± 10.2 years and males were represented 60% (30) of patients.                The majority of patients were had hypertension (72%) and Diabetes Mellitus (56%). Among control group, only 8 patients were had hypertension while DM was presented in 29 (58%) patients. The mean HbA1C across patients was 8.02 ± 2.5, which was significantly higher in comparison to mean HbA1C across control group. The assessment of National Institutes of Health Stroke Scale score across patients showed that, a significant higher HbA1C among severs and moderate NHISS in comparison to mild NIHSS. Also, all mild NIHSS patients were in control status for HbA1C, while all severe NIHSS patients were uncontrolled. The distribution of HbA1C group was not equally across NIHSS. The multinomial logistic regress test showed, apart from HbA1C, which showed a strong association with NHSS,                  no association have been found between NHSS and other variables.
CONCLUSION:
A high HbA1C was associated with high NIHSS score in patients with stroke. There was a risk of 3.1 fold increase of stroke in patients with uncontrolled HbA1C.