Authors
1
Neurosciences hospital
2
/ Al-Mustansiriya College Of Medicine/ Baghdad/Iraq.
3
/ Al-Mustansiriyah College Of Medicine/ Baghdad/Iraq.
,
Document Type : Research Paper
Abstract
Abstract
Background: Gamma knife radiosurgery, a bloodless surgery used to treat a variety of intracranial pathologies and is regarded as the first line for treating trigeminal neuralgia, since it has the property of minimal invasiveness and risk.
Aim: In this report, we estimate the effect of gamma knife radiosurgery on certain inflammatory markers in patients with TN.
Materials and Methods:
29 patients underwent gamma knife radiosurgery for TN between September 2018 to March 2019. Two readings of inflammatory biomarkers were recorded, the first one just prior to GNRS while the second within one month after it.
Statistical Analysis: Statistical analysis was performed using the Microsoft Excel Statistical Package
Results: the measured data for each gender is considered separately since TN is more common among women than men. significant changes were observed regarding PDW and Lymphocytes level post radiosurgery in female group (n=19) but not in male
Conclusion: the significant decrement in PDW and lymphocyte cell percentage post radiosurgery supports the inflammatory hypothesis in trigeminal neuralgia
Results: the measured data for each gender is considered separately since TN is more common among women than men. significant changes were observed regarding PDW and Lymphocytes level post radiosurgery in female group (n=19) but not in male
Conclusion: the significant decrement in PDW and lymphocyte cell percentage post radiosurgery supports the inflammatory hypothesis in trigeminal neuralgia
Keywords
Trigeminal neuralgia, gamma knife, PDW
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