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Evaluation of Haematological parameters in patients with Covid 19 infection in Nineveh Province

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Document Type : Research Paper

Abstract

Background: In December 2019, a novel virus later named severe acute respiratory syndrome coronavirus-2 was isolated from the broncho-alveolar fluid of a patient in Wuhan, suffering from what became known as coronavirus disease 2019 (COVID-19). The first case was registered in Nineveh Province on March 22, 2020. Diagnosis was made by molecular identification of severe acute respiratory syndrome coronavirus-2 by polymerase chain reaction. So , clinical, haematological, and haemoststic parameters should take in account as they are important in determining the severity of the illness and outcome. This study focus on haematological and some haemostatic parameters in 100 cases with positive polymerase chain reaction.
Aim of study: To evaluate the haematological parameters “CBC” in patients with COVID 19 infection and to study some of the changes in first line of coagulation parameters.
Patients &methods: The current study is a case series study involving 100 patients admitted to Al-Shifaa hospital in Mousl city in the period between February 2021 and August 2021 involved collection of data, blood samples and laboratory investigations. The investigations include: complete blood count and coagulation parameters “prothrombin time (PT)” , “activated partial thromboplastin time (APTT)” , and “D.dimer”.
Results: Out of 100 patients encompasses , 51 were males, 49 were females with the age range between 10-87 years. The patients presented with a wide range of symptoms, fever and cough were the most common complains. “Lymphopenia” was the most common haematological abnormality (74%). “D.dimer” was the most common coagulation abnormality (31%). Smokers run mild to moderate course of illness.
Conclusion: Monitoring haematological and haemostatic parameters in patients with severe acute respiratory syndrome coronavirus-2 infection can predict the severity of the course of the disease and outcome of the patients.

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References

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Iraqi Postgraduate Medical Journal
Volume 23, Issue 3
July 2024
Page 369-476
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