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The effect of pediatric pyeloplasty in poorly functioning kidneys with Split renal function between 10% to 20%: A single institute experience

    Authors

    • Yasir Fathi Al Shatari 1
    • Yousuf Mohammed Al Hallaq 2

    1 urology specialist , Al Karama hospital , Baghdad

    2 Head of urology department in medical city complex

,

Document Type : Research Paper

10.52573/ipmj.2025.145552
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Abstract

Background: Management of poorly functioning kidneys with ureteropelvic junction obstruction (UPJO) is controversial, with some recommending direct nephrectomy and others direct pyeloplasty, and others temporary diversion.
Aim of the study: to determine the outcome and whether pyeloplasty allows for functional recovery in poorly functioning kidneys in the pediatric age group.
Patient & method: A prospective review of 25 patients with unilateral UPJO who underwent open Anderson-Hynes pyeloplasty (AHP) with a split renal function (SRF) 10-20% at Baghdad Medical City for the period between December 2019 to September 2022 was conducted, the changes in the SRF measured by MAG-3 study after 1-year were compared.
Results: our study included 25 patients divided into two groups below (52%) and above (48%) 1-year-old with preoperative SRF 10%-20% of the affected side, Success was defined based on either improvement in symptoms, improvement in drainage on postoperative diuretic renography, and/or improvement or stability in SRF on the renal scan done 12 months postoperatively.
Deterioration of SRF by more than 5% was deemed a Failure. An increase in SRF of more than 5% was deemed an improvement. (17)
Mean preoperative SRF was 15.4±2.8% in all cases, which increased postoperatively in the success group from 15.5±2.9% to 23.7±4.7%, and this improvement was highly significant, while in two cases with failure with SRF from 13.5±2.1% to 5.5±2.1%.
The success rate was 92%, whereas a secondary nephrectomy was necessary for two (8.0%).
Conclusion: Poorly functioning renal units with SRF 10% - 20%, can show functional improvement and recoverability, so in these renal units, we can’t rush to do a nephrectomy instead, we can proceed to pyeloplasty.

Keywords

  • ureteropelvic junction (UPJ) obstruction
  • pyeloplasty
  • nephrectomy
  • mercapto-acetyl-tri-glycine study (MAG-3)

Main Subjects

  • Urology
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References
  1. Partin AW, Wein AJ, Kavoussi LR, Peters CA, Dmochowski RR. Campbell Walsh Wein Urology, E-Book. Elsevier Health Sciences; 2020 ;Chapter 42:826-27.
  2. Snodgrass WT. Pediatric urology. Springer-Verlag New York; 2016. Chapter 11 ureteropelvic obstruction; 2013:165-80.
  3. Bomalaski MD, Hirschl RB, Bloom DA. Vesicoureteral reflux and ureteropelvic junction obstruction: association, treatment options and outcome. The Journal of Urology. 1997;157:969-74. https://doi.org/10.1016/S0022-5347(01)65121-8
  4. Passoni NM, Peters CA. Managing ureteropelvic junction obstruction in the young infant. Frontiers in Pediatrics. 2020;8:242. https://doi.org/10.3389/fped.2020.00242
  5. Smith JA, Howards SS, Preminger GM, Dmochowski RR. Hinman's Atlas of Urologic Surgery E-Book. Elsevier Health Sciences; 2016 Dec 26.
  6. Salih E, Abdelmaksoud I, Elfeky M, Selmy G, Galal H, Zekry M. Renal functional improvement after pediatric pyeloplasty in kidneys with split renal function less than 20%: a single institute experience. Annals of Pediatric Surgery. 2021;17:1-6. https://doi.org/10.1186/s43159-021-00084-w.
  7. Abdelaziz AY, Shaker H, Aly H, Aldaqados H, Hussein EM. Early outcome of pediatric pyeloplasty in kidneys with split renal function less than 10%: A prospective study of 25 cases. African Journal of Urology. 2018;24:324-30. https://doi.org/10.1016/j.afju.2018.08.003
  8. Pramod S, Ramji AN. Clinical profile and outcome of pelvi-ureteric junction obstruction (PUJO) in children presenting above 1 year. International Surgery Journal. 2018;5:3066-71. https://doi.org/10.18203/2349-2902.isj20183724
  9. Gnech M, Berrettini A, Lopes RI, Moscardi P, Esposito C, Zucchetta P, Dénes FT, Manzoni G, Braga LH, Castagnetti M. Pyeloplasty vs. nephrectomy for ureteropelvic junction obstruction in poorly functioning kidneys (differential renal function< 20%): a multicentric study. Journal of Pediatric Urology. 2019;15:553-e1. https://doi.org/10.1016/j.jpurol.2019.05.032
  10. Lone YA, Samujh R, Bhattacharya A, Kanojia RP. Outcome of poorly functioning kidneys secondary to PUJO preserved by pyeloplast. Journal of Pediatric Surgery. 2017;52:578-81. https://doi.org/10.1016/j.jpedsurg.2016.11.039
  11. Menon P, Rao KL, Bhattacharya A, Mittal BR. Outcome analysis of pediatric pyeloplasty in units with less than 20% differential renal function. Journal of Pediatric Urology. 2016 ;12:171-el. https://doi.org/10.1016/j.jpurol.2015.12.013
  12. Suresh S, Jindal S, Duvuru P, Lata S, Sadiya N. Fetal obstructive uropathy: impact of renal histopathological changes on prenatal interventions. Prenatal diagnosis. 2011;31:675-77. https://doi.org/10.1002/pd.2798.

 

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Iraqi Postgraduate Medical Journal
Volume 24, Issue 1
January 2025
Page 61-70
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APA

Al Shatari, Y., & Al Hallaq, Y. (2025). The effect of pediatric pyeloplasty in poorly functioning kidneys with Split renal function between 10% to 20%: A single institute experience. Iraqi Postgraduate Medical Journal, 24(1), 61-70. doi: 10.52573/ipmj.2025.145552

MLA

Yasir Fathi Al Shatari; Yousuf Mohammed Al Hallaq. "The effect of pediatric pyeloplasty in poorly functioning kidneys with Split renal function between 10% to 20%: A single institute experience". Iraqi Postgraduate Medical Journal, 24, 1, 2025, 61-70. doi: 10.52573/ipmj.2025.145552

HARVARD

Al Shatari, Y., Al Hallaq, Y. (2025). 'The effect of pediatric pyeloplasty in poorly functioning kidneys with Split renal function between 10% to 20%: A single institute experience', Iraqi Postgraduate Medical Journal, 24(1), pp. 61-70. doi: 10.52573/ipmj.2025.145552

VANCOUVER

Al Shatari, Y., Al Hallaq, Y. The effect of pediatric pyeloplasty in poorly functioning kidneys with Split renal function between 10% to 20%: A single institute experience. Iraqi Postgraduate Medical Journal, 2025; 24(1): 61-70. doi: 10.52573/ipmj.2025.145552

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