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The Correlation of Anti-mullerian hormone (AMH) level with anthropometric measurements in premenopausal women

    Authors

    1 Ministry of health/ public health department/central public health laboratory

    2 Minisrty of health / public health department/ central public health laboratory

    3 Ministry of health / public health department / central public health laboratory

,

Document Type : Research Paper

Abstract

Background :
Anti-Müllerian hormone (AMH) can serve as a good biomarker for the ovarian reserve that can predict female fertility, studying the biological factors that impact AMH levels is necessary for predicting reproductive health outcomes . Obesity (general obesity by body mass index and central obesity by waist circumference), is associated with negative reproductive outcomes that could be related to its impact on AMH level . Female fecundity begins to decrease after women reach the age of 30 years for multifactorial causes that could be hormonal changes .
Objective :
The study aims to find the association of Anti-mullerian hormone (AMH) level , as a biomarker for ovarian reserve , with general and central obesity , and other anthropometric measurements in premenopausal women.
Subjects and Methods :
This is a descriptive cross sectional study enrolled a total of 270 Iraqi women in the reproductive age . Height ,Weight and Waist Circumference were measured for all participants .Serum AMH has been analyzed using Enzyme Linked immunofluorescence Assay technique (ELFIA). Subjects were divided into three groups according to their body mass index BMI, and into two groups depending on WHO criteria for central obesity, and into three groups according to their susceptibility to metabolic risk, and into four groups according to their age. Statistical analyses were performed using SPSS software.
Results :
AMH level was significantly lower in obese and overweight women than in normal weight women. women with increased and substantially increased risk for metabolic complication have significantly lower AMH level than those with no metabolic risk.
Same for women with central obesity than those without it and married women than in singles.
Conclusion :
AMH has a negative association with Body mass index , Waist Circumference , and age .

Keywords

Main Subjects

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Iraqi Postgraduate Medical Journal
Volume 24, Issue 1
January 2025
Page 147-155
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