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Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage

    Authors

    • Omar Mahmoud Shaker 1
    • Hasan Aziz Al-Hamadani 2

    1 Diyala Director of health

    2 College of Medicine. Al-Nahrain University.

,

Document Type : Research Paper

10.52573/ipmj.2025.157167
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Abstract

ABSTRACT:

BACKGROUND:

Intracerebral hemorrhage (ICH) is a critical and debilitating form of stroke, affecting over one million people globally each year. Recent research has focused on exploring the role of C-reactive protein (CRP) in ICH cases.

OBJECTIVE:

This study aimed to investigate the association between CRP levels and the severity of spontaneous ICH.

PATIENTS AND METHODS:

A cross-sectional study was conducted at Al-Imamein Al-Kadhimein Medical City and Al-Yarmouk Teaching Hospital. It included patients aged 18 years or older with a primary diagnosis of ICH within 48 hours of symptom onset.

RESULTS:

A total of 107 patients with acute ICH were included. The majority (57%) were aged 46–65 years, with a mean age of 58.65 years. Males accounted for 66.4% of cases. Elevated CRP levels (>10 mg/L) were observed in 63.6% of patients, with a mean CRP of 37.32 mg/L. The average ICH score was 1.14, and most cases (37.4%) had an ICH score of 1. A Glasgow Coma Scale (GCS) range of 13–15 was most common, with a mean GCS of 12.95.

CONCLUSION:

CRP levels in ICH patients were not significantly correlated with GCS, ICH scores, or mortality risk, suggesting a limited role in acute severity.

Keywords

  • KEYWORDS: CRP
  • intracerebral hemorrhage
  • severity

Main Subjects

  • Neurology
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Iraqi Postgraduate Medical Journal
Volume 25, Issue 1
January 2026
Page 87-93
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APA

Shaker, O., & Al-Hamadani, H. (2025). Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage. Iraqi Postgraduate Medical Journal, 25(1), 87-93. doi: 10.52573/ipmj.2025.157167

MLA

Omar Mahmoud Shaker; Hasan Aziz Al-Hamadani. "Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage". Iraqi Postgraduate Medical Journal, 25, 1, 2025, 87-93. doi: 10.52573/ipmj.2025.157167

HARVARD

Shaker, O., Al-Hamadani, H. (2025). 'Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage', Iraqi Postgraduate Medical Journal, 25(1), pp. 87-93. doi: 10.52573/ipmj.2025.157167

VANCOUVER

Shaker, O., Al-Hamadani, H. Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage. Iraqi Postgraduate Medical Journal, 2025; 25(1): 87-93. doi: 10.52573/ipmj.2025.157167

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