Abstract
Background: Genodermatoses are inherited skin disorders with variable expressivity and high morbidity. Their epidemiology and expression show regional variation due to genetic and environmental influences.
Objectives: To record genodermatoses' clinical and epidemiological characteristics among patients attending the Baghdad Dermatology Centre of Medical City in Baghdad. We also aim to shed light on regional factors, such as consanguinity and genetic trends, among the patients.
Patients and Methods: This cross-sectional study was conducted from April 2022 to August 2023. Clinical patients with a diagnosis of genodermatoses were evaluated, and demographic data, clinical characteristics, and pedigree analysis were performed on them.
Results: Generalised skin lesions were most common (55.6%), followed by the extremities (30.9%), the scalp/face (24.7%), and the trunk (17.3%). There was a strong association between consanguinity (66.7%) and a positive family history (54.3%), respectively. Patterns of prevalence were observed by sex and age.
Conclusion: These results highlight the importance of genodermatoses as a health burden in Iraq in consanguineous families. According to the study, genetic studies and management initiatives are critical for implementing early diagnosis and management strategies.
Main Subjects
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