Abstract

ABSTRACT :
BACKGROUND:
Helicobacter pylori is recognized as an important human pathogen by virtue of its association with
peptic ulcer disease , gastric cancer , gastric lymphoma and high prevalence of infection
worldwide. Recently this organism was detected in tonsil and adenoid tissue after
adenotonsillectomy , as well as in mucosa of patients with chronic rhinosinusitis , but its
association with simple nasal polyposis has not been investigated yet in our country .
OBJECTIVE:
To investigate a possible contribution of Helicobacter pylori (H.pylori) in the etiopathogenesis of
simple nasal polyps .
Study Design: Prospective clinico –pathological investigation.
METHODS :
Twenty eight patients with nasal polyposis were studied for the presence of Helicobacter pylori in
the nasal polyp specimens by histopathological examination of serial sections stained by modified
Giemsa stain .
RESULTS:
Helicobacter pylori was detected in 10 (35%) of total 28 simple nasal polyps specimens.
CONCLUSION:
This study found a significant percentage 10/28 patients (35%) with Helicobacter pylori infection
in nasal polyps and to confirm the role of Helicobacter pylori in the etiopathogenesis of nasal
polyposis , extensive epidemiological studies would be necessary