Abstract
ABSTRACT:
BACKGROUND:
Pre-labour rupture of the membrane is a common clinical problem, and the assessment of the woman with possible membrane rupture is management issue faced in every day practice. When premature rupture of membrane (PROM) occurs, the fetus loses the relative isolation and protection afforded within the amniotic cavity.
OBJECTIVE:
To evaluate the reliability of vaginal washing fluid Beta-human chorionic gonadotropin for the detection of premature rupture of membrane and to determine a cut-off value.
METHOD:
A prospective case-study includes 79 pregnant women subdividing into three groups (groupA: 20 pregnant women with confirmed premature rupture of membranes, group B: 19 pregnant women with suspected premature rupture of membranes, group C: apparently healthy pregnant women without any complaint) for which speculum examination for amniotic pooling, nitrazine paper test, measurement of vaginal washing fluid Beta-human chorionic gonadotropin were performed.
RESULTS:
There was significant differences in mean vaginal washing fluid β-HCG concentration among the three groups (p= 0.000), being higher in group A than the other two groups and the time interval between sampling and delivery was significantly shorter among patient in group A than group B and C.
CONCLUSION:
Vaginal fluid β-HCG determination is reliable, simple and rapid test for the detection of PROM.
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