Abstract

ABSTRACT:
BACKGROUND:
Thyrotoxicosis is one of the most common presentations in thyroid disease, Graves’ disease, multinodular goiter, toxic adenoma and thyroiditis are its main common causes, almost every system is affected and there is great individual variation in the dominant features.
OBJECTIVE:
The study objectives are to explore the pattern of thyrotoxicosis in Sulaimania city during the years1996-2006.
METHODS:
From January1996 to January 2006,452 thyrotoxic cases 165 males and 287 females were evaluated for the causes, history of iodine prophylaxis program ,their manifestations, the eye signs and relation of the smoking with the eye signs.
RESULTS:
Analysis of 452 patients proved to have thyrotoxicosis by thyroid function tests, females were 64% and males 36%, the mean age was around 39 years, graves’ disease was the cause in 59.51% of the cases, followed by Iodine-induced thyrotoxicosis 21.9%, multinodular goiter 9.96%, single nodule goiter 7.97%, then finally subacute thyroditis 0.66%,Among the thyrotoxic cases 61.06% has weight loss and 50% has hand tremor , in those with eye sign 56% has non-infiltrative and44% has infiltrative eye signs.
CONCLUSION:
Thyrotoxicosis is twice more common in females than males, Graves’ disease is the commonest cause while iodine induced thyrotoxicosis is another important cause in the setting of iodine prophylaxis program, weight loss and hand tremor are commonest manifestation. In between ophthalmopathic smokers infiltrative eye signs were more common than non infiltrative.