Abstract

ABSTRACT:

There is an increasing interest in the role of genetics in many urological diseases and malfunctions. The door was opened for early diagnosis, application of genetically based armamentarium to prevent, treat or modify the clinical course as well as prediction of the prognosis of such abnormalities.
Many urologists share the idea that the use of a genetic tool to diagnose or treat their patients still has a long time before coming into a real clinical and surgical practice.
The purpose of this article is to briefly and simply review gene therapy, epigenetic therapy and stem cell therapy principles and prospects in the management of various urological disorders and to encourage standard urology centers' authorities in the Middle East countries to develop, share and improve their national experience which can serve genetic counseling and possible therapeutic management of their own patients to cope with the international revolution in this field