Abstract

Vitamin B12 deficiency in infants often produces
haematological and neurological deficits, including
macrocytic anaemia ,neurodevelopmental delay or
regression, irritability, weakness ,hypotonia ,
ataxia, apathy, tremor, and seizures. The diagnosis
of vitamin B12 deficiency can be difficult when
the typical macrocytic anaemia is absent
)

Infantile vitamin B-12 deficiency with ineffective
haematopoiesis and degeneration of nervous tissue
has been reported in breast fed infants of mothers
on strict vegetarian diets
2) )
Adults may tolerate
vitamin B-12 deficient diets for many years
without apparent symptoms due to their
endogenous stores. In contrast, infants have very
limited hepatic reserves of vitamin B-12 and so
may develop symptoms of deficiency within
month's
2)

(
. we report two cases in which they were
diagnosed as cerebral palsy in early life. first case
was 9 month old female baby presented with
pallor for last 3 months of age, floppiness ,regress
of acquired millstone ,exclusive breast feed for a
vegan mother ,diagnosed as megaloblastic anemia
second case was 16 months old male baby
presented with apathiness , he was exclusively
breast feed till this age with minimum
complementary food.
KEY WORDS : megloblstic anemia ,breast feed